mass spectrometry (MS) - Blogging About What's Possible

Recent posts

Comprehending COVID-19: How Consumables Can Increase LC-MS/MS Sensitivity

By January 19, 2021

During 2020, we collaborated with many of our customers to develop targeted liquid chromatography–mass spectrometry/mass spectrometry (LC-MS/MS) methods to detect SARS-CoV-2 (the virus that causes COVID-19) from biological samples. However, the combination of the biological… Read more >

Categories: Chemical, COVID-19, Technologies
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Nuts About Christmas … And Mycotoxin Detection

By December 21, 2020

A bowl of nuts, with polished or carved nutcrackers, is part of many traditional winter holiday feasts. Growing up in England in the 1970s, I enjoyed hazelnuts, almonds, walnuts and Brazil nuts as special treats… Read more >

Categories: Food & Environmental
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Oil: A Source of Light and Cause for Celebration

By December 8, 2020

The use of light during holidays or festivals – in any form, including candles, lanterns, or fireworks – is significant, as we celebrate and look ahead to the future. Many friends and colleagues recently celebrated… Read more >

Categories: Food & Environmental
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USEPA Approves APGC Tandem Quadrupole Mass Spectrometry as Alternative Test Procedure for Dioxin Analysis

By November 19, 2020
Waters Atmospheric Pressure Gas Chromatography system with the Xevo TQ-XS (APGC-MS/MS) platform

A Breakthrough in Dioxin Analysis for Environmental Laboratories In September, the United States Environmental Protection Agency (USEPA) recognized the use of atmospheric pressure gas chromatography (APGC) with tandem quadrupole mass spectrometry (MS) as an acceptable… Read more >

Categories: Food & Environmental, Technologies
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Reveal Molecular Secrets – and Set Them to Work!

By June 23, 2020

From fundamental research to routine analysis, Waters’ latest innovations in mass spectrometry enable our customers to gain – and apply – insights across the scientific spectrum. Beginning with fundamental research where the focus is on… Read more >

Categories: Pharmaceutical, Technologies
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Waters and the University of Tokyo Collaborate on Lipidomics Research

By February 28, 2020

Digging deep into the human biome, Professor Yoshiya Oda of the Graduate School of Medicine at the University of Tokyo looks to ion mobility technology to uncover deposits of insight It’s an established fact that… Read more >

Categories: Biomedical Research, Technologies
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Mobile Phase Additives for Peptide Characterization

By October 2, 2019

The characterization of peptides and proteins can be challenging due to issues such as adsorption, varying hydrophobicities, and specificity to name just a few. When analyzing peptides by Liquid Chromatography (LC) and Mass Spectrometry (MS),… Read more >

Categories: Chemical
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Learning from User Experience

By May 8, 2019

What does “intelligence” mean in the context of biopharma analysis? Given the complex setting, much of the answer comes down to the task a user needs to complete, along with the question of who exactly… Read more >

Categories: Pharmaceutical, Technologies
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The Expanding Role of Mass Spec for Peptide Mapping in Multi-Attribute Monitoring Assays

By July 12, 2018

There are two primary multi-attribute monitoring (MAM) assay choices for biologic development and QC: subunit protein mass analysis and peptide mapping by LC-MS. Here we explore how peptide mapping LC-MS MAM workflows are being used.

Categories: Pharmaceutical
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Multi-Attribute Monitoring: The Expanding Role of Mass Spectrometry for mAb Subunit Analysis

By June 1, 2018

Two MAM approaches for biotherapeutic analysis are being implemented today; one focused on the analysis of monoclonal antibody (mAb) subunits, and the other focused on the analysis of peptides from a protein digest (peptide mapping workflow). Both have their advantages and disadvantages. Here, we explore MAM for mAb subunit analysis.

Categories: Pharmaceutical
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