How to choose the best stationary phase for polar compounds

Retaining and separating highly polar, water-soluble organic compounds has historically been a challenge for separation scientists who prefer reversed-phase chromatography as their technique of choice. There are many reasons why a conventional RP columns are not ideal for polar compound retention. However, let’s not dwell on the problems of the past; the development of T3 bonded particles have changed that!

T3 Particle Technology was developed using optimized C₁₈ ligands and proprietary end-capping to create the ideal column characteristics for polar compound retention.

Available in three stationary phases based on unique particle substrates, CORTECS Solid-Core T3, ACQUITY UPLC/XSelect HPLC HSS T3, and Atlantis silica T3 columns provide enhanced polar compound retention and longer column lifetimes in reversed-phase separations.  

Our infographic can help you choose the best stationary phase to master your polar compound retention work.

More resources:

• Download the white paper:  Designing Reversed-Phase Columns for Polar Compound Retention
• Watch our on-demand webinar: Polar Compound Retention – Understanding What Works, What Doesn’t Work, and What’s New In Reversed-Phase Polar Compound Retention
• Download the Atlantis Application Notebook