Get Empowered: Tip #230 | Working with QDa Data
Tip #230: Working with QDa Data in Empower
In this week’s tip, we review working with QDa data in Empower
The QDa mass detector can collect 2D SIR data and/or 3D scan data analogous to the PDA detector. I’ve had numerous questions recently about working with QDa data and thought it was a good time to revisit this topic (Refer to Tips #100 & 101, 103-119, 123, and 56-62 for more detail).
Here are a few highlights of the topics we’ve covered.
Let’s get started.
When using a PDA and QDa mass detector in series, you can obtain base peak (m/z) from the peaks in the UV chromatogram using a PDA Processing Method (figure 1).
While working with the UV chromatogram, you can view both UV and MS spectra for the peaks in the Mass Analysis window. (Be sure to correct for the offset between the two detectors) (figure 2).
CODA, or Component Detection Algorithm, is a mathematical algorithm which helps extract peaks from noisy TIC plots (figure 3).
Component based expected mass processing is done by entering the expected masses for the components in the Processing Method (figure 4).
MS Peak Tracking is useful when doing method development and you want to track your peaks by Assigned Mass (figure 5).
Other actions include injection based expected mass processing, creating MS libraries to help
identify peaks, and calculating MS Ion ratios.
It’s that easy!
Final Note: You can use either the Pro or QuickStart interface for this tip.
Learn more about the ACQUITY™ QDa™ Mass Detector and take advantage of our special ACQUITY™ QDa™ offer
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Next week in Empower Tip #231: I will answer another Empower user question about setting a Minimum Area for Group Peaks.
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