Recent posts

High-throughput Microscale Bioanalysis is not a Paradox

By May 21, 2016

  Question: When someone says microscale chromatography, what comes to mind? Increased sensitivity? Reduced sample volume? Enhanced MS sampling efficiency? Yes, yes, and yes! You might also say, “finicky,” “slow,” or “only one person in… Read more >

Categories: Pharmaceutical, Technologies
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Tof-HRMS: Rescuing Low-Exposure Bioanalysis Applications from Chemical Noise

By April 18, 2016

The drug development process requires pharmacokinetic (PK) analysis to be performed as part of safety and efficacy studies in both preclinical species and human subjects. For high-sensitivity bioanalysis, liquid chromatography (LC) coupled to a triple… Read more >

Categories: Chemical, General, Pharmaceutical, Technologies
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Is Ion Mobility Mass Spectrometry Child’s Play?

By December 4, 2015

On Wednesday evening after dinner and my usual digestif, I was watching the webcast “Making Ion Mobility Mass Spectrometry Routine” when my son walked by. “Wow dad, that’s kind of cool! What the heck is… Read more >

Categories: General, Pharmaceutical, Technologies
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Microflow LC-MS in Early Discovery through Development

By April 23, 2015

Let’s face it. Microflow LC-MS is a challenge. Only a few do it well, and even fewer do it well consistently. And for those who have had success, their methods can completely fall apart when… Read more >

Categories: Health Sciences, Pharmaceutical, Technologies
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Have we bridged the gap between qual and quan using HRMS?

By March 2, 2015

Increasing Size, Complexity and Potency: The Bioanalytical Challenge of the Next Decade, was the theme for the 3-day APA India held in Mumbai, India from February 23-25, 2015. Close to 300 attendees gathered to discuss… Read more >

Categories: Pharmaceutical, Technologies
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