Recent posts

Second Tier Newborn Screening Tests – Improving the Specificity of One of the Greatest Public Health Achievements

By January 29, 2019

Newborn screening for inherited disorders has been heralded as one of the 10 greatest public health achievements of the first decade of the 21st century.1 The ability to pre-symptomatically identify newborn babies at risk of… Read more >

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National Newborn Screening Programs: An Overview of Challenges and Successes

By November 28, 2018

Don Mason reviews the state of newborn screening (NBS) programs around the world.

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11th ISNS European Regional Meeting, Bratislava Slovakia; An Overview

By October 30, 2018

Reflecting on a common concern in newborn screening: Reliability.

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Advancing Diagnostic Screening with the RenataDX Screening System

By October 11, 2018

Waters’ legacy of purposeful innovation continues with the recently introduced RenataDX Screening System, a flow-injection tandem mass spectrometry system for high-throughput analysis of extracted dried blood spots and other physiological matrices.

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The Historical Role of Mass Spectrometry in Newborn Screening

By September 24, 2018

Newborn screening for inherited metabolic disorders dates to the early 1960s when Dr. Robert Guthrie in Buffalo, New York developed the first screening test for phenylketonuria (or PKU), a metabolic disease in which patients can’t metabolize the amino acid phenylalanine.

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Why Tandem Mass Spec is Essential for Newborn Screening

By September 7, 2018

Mass spectrometry has been game changer in newborn screening because rather than having a single test for a single condition, there was now a technique that provided a single test for a large number of different conditions.

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