When considering that the range of compounds that might be subject to chromatography goes from highly volatile species with molecular weights of tens of Daltons, to proteins with molecular weights of hundreds of thousands of Daltons, maybe it isn’t so surprising that there are a variety of separation techniques required.
With Empower Tip #83, we continue looking at Custom Fields and learn how to create a Custom Sample Set Field. A Sample Field is something that identifies a sample and each sample can have its own set of unique identifiers. A Custom Sample Set Field is something that identifies the entire Sample Set. Common Custom Sample Set Fields are method type, column used, and mobile phase used.
Tip #82: How to create a Custom Field in Empower Welcome back to Get Empowered! In the last Empower tip-of-the-week post for Empower CDS Software, we learned about using the Result Audit Viewer to understand the… Read more >
If someone has generated multiple results for a sample, it is important to understand what the differences are between those results. Using the Result Differences table in Empower Software’s Result Audit Viewer makes the job much easier. Let’s see how it’s done!
We listened and learned how scientists separate mAbs and ADCs; then we designed a novel column for LC-MS bioseparations A critical step toward the prolific and successful use of monoclonal antibodies (mAb) as biotherapeutics occurred… Read more >
Empower Software’s Result Audit Viewer makes it easier to review the audit trail information associated with a Result Set by bringing this information into one window rather than going to all of the individual audit trail windows. In this tip, we take a tour of the Result Audit Viewer.
We answer a question as a follow-up to Tip #74 on using Empower’s System Suitability option to calculate the ratio of peak to valley height when there’s a valley between the chromatographic peaks; What about calculating valley height when there are two fused peaks?
Analytical methods transfer. Data integrity. A changing and more stringent regulatory landscape. All this, and more, impacts productivity in upstream and downstream biopharmaceutical processes. How is Waters looking to help address development challenges for biologics and biosimilars?
Halting a chromatographic analysis where the system is not performing correctly or when another error is evident in the separation is a valuable and scientific way to avoid creating unusable data that needs to be subsequently invalidated following a defined analytical lab error/result SOP. But what do you do with that orphan data?
Lots of questions about calculating impurities in Empower Software! Here’s another answer to a reader who inquired: How do you quantitate impurities against the main component? We’re happy to show how…