Recent posts

Webinar Highlights: Quantifying Cannabinoids in Oral Fluid to Determine Driving Impairment Following Marijuana Consumption

By June 1, 2018

Q&A from a recent forensic toxicology webinar on using an ACQUITY UPLC I-Class/Xevo TQ-S micro MS system for quantifying cannabinoids in oral fluid.

Categories: Health Sciences
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Multi-Attribute Monitoring: The Expanding Role of Mass Spectrometry for mAb Subunit Analysis

By June 1, 2018

Two MAM approaches for biotherapeutic analysis are being implemented today; one focused on the analysis of monoclonal antibody (mAb) subunits, and the other focused on the analysis of peptides from a protein digest (peptide mapping workflow). Both have their advantages and disadvantages. Here, we explore MAM for mAb subunit analysis.

Categories: Pharmaceutical
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Get Empowered: Review Window and the Processing Method | Tip #71, System Suitability

By May 30, 2018
Empower tip-of-the-week

#71: Learn how Empower CDS calculates Detector Noise and Drift using the System Suitability option.

Categories: Empower Tip-of-the-Week
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Get Empowered: Review Window and the Processing Method | Tip #70, System Suitability

By May 23, 2018
Empower tip-of-the-week

#70. Using the System Suitability Option, learn how Empower Software calculates Baseline Noise and Drift. This can be useful if you are not in a regulated laboratory environment when you probably want to calculate Signal to Noise without the USP, EP, or JP formula.

Categories: Empower Tip-of-the-Week

How to Detect Fipronil in Eggs: Tips for Pesticide Screening Laboratories

By May 22, 2018

We discuss analytical options using LC and GC with MS/MS to detect the pesticide fipronil in eggs for food safety testing.

Categories: Customer Stories, Food
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How to improve analytical method transfers for biotherapeutics

By May 21, 2018

“Assuming continuous improvement is a worthy goal, there is every reason to improve validated chromatographic methods if you’re working with the right instrument technology,” says Eric Grumbach of Waters. See what that means for developing and transferring methods for biologic drugs.

Categories: Pharmaceutical
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Get Empowered: Review Window and the Processing Method | Tip #69, System Suitability

By May 16, 2018
Empower tip-of-the-week

#69: Learn how Empower Software calculates Peak-to-Peak Noise for USP, EP, and JP Signal-to-Noise calculations.

Categories: Empower Tip-of-the-Week
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Setting a New Standard for Reserved-Phase Separations of Monoclonal Antibodies and Antibody Drug Conjugates

By May 15, 2018

A new approach to stationary phase chemistry for reversed-phase LC analysis of proteins, including monoclonal antibodies and antibody drug conjugates, delivers higher fidelity data especially for MS-based peak identification.

Categories: Columns
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Columns Matter, Too: Choosing Optimal Conditions for Trap-and-Elute Nanoflow and Microflow LC-MS

By May 14, 2018

Considerations for optimizing trapping conditions, such as flow rate and trapping volume, in nanoscale and microflow LC-MS.

Categories: Technologies
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Get Empowered: Review Window and the Processing Method | Tip #68, System Suitability

By May 9, 2018
Empower tip-of-the-week

We begin a multi-part discussion about the System Suitability option in Empower Software, starting with what are Statistical Moments and how are they helpful.

Categories: Empower Tip-of-the-Week
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