Get Empowered: Review Window and the Processing Method | Tip #72, System Suitability

By June 5, 2018


Tip #72: Working with the System Suitability Option (Part 5)

Welcome back to Get Empowered! In our last tip-of-the-week blog for Empower Software, we learned about how Empower calculates Detector Noise and Drift (Tip #71)

Working with Empower Software’s System Suitability option:

In this weeks’ tip, we are going to learn about Acceptance Criteria Limits in the Processing Method (Part 5).

In Tip #27, we learned how to use the Suitability Limits to flag results that are outside of a desired range. What about the Acceptance Criteria Limits on the Limits tab? What is it and when would it be used?

As an example, we can use the Acceptance Criteria Limits to check limits between chromatograms without needing to create custom fields. It may also be the case that you do not have the software privileges to create custom fields. Not to worry, this is very easy to do in the Processing Method.

Let me show you how it is done.

Step 1

We begin by bringing a Sample Set into Review, open a Processing Method, and Integrate/Calibrate a channel for a standard (Figure 1). The %Area for the Ethyl Paraben peak is 35.44. We are going to set the Acceptance Criteria Limit for this peak to be a %Area greater than or equal to 35.00.

Empower Tips: Open a Processing Method and Integrate/Calibrate a channel for a standard | Figure 1

Figure 1

Step 2

Go to the Processing Method window, click the Limits tab, and highlight Ethyl Paraben in the Suitability Components table. Then click in the Field Name in the Acceptance Criteria Limits table and select %Area (Figure 2).

Empoer Tips: Limits tab | Figure 2

Figure 2

Step 3

Click in the Left Side field and the Formula Entry window opens. Either type or double-click on %Area to add it to the Field area (Figure 3). Then click Finish.

Empower Tips: Formula Entry window | Figure 3

Figure 3

Step 4

Select GTE from the Operation list (Figure 4).

Empower Tips: Select GTE / Operation list | Figure 4

Figure 4

 Step 5

Click in the Right Side field and, when the Formula Entry window opens, enter 35.00 and click Finish (Figure 5).

Empower Tips: Formula Entry window | Figure 5

Figure 5

 Step 6

Enter a precision of 2, select Error from the Warning/Error drop-down list, and select During Quantitation from the Check Relative Limits drop-down list (Figure 6).

Empower Tips: Warning/Error drop down list/Check Relative Limits drop down list | Figure 6

Figure 6

 Step 7

Save the Processing Method, return to the Main Window, and integrate/quantitate one of the samples (Figure 7). We see that the %Area for Ethyl Paraben is 36.21, which meets the criteria.

Empower Tips: Main Window/Integrate/quantitate one of the samples | Figure 7

Figure 7

 Step 8

The next sample shows a %Area for Ethyl Paraben of 34.25, which is below the limit, and it’s flagged (Figure 8).

Empower Tips: Limit below is flagged | Figure 8

Figure 8

 Step 9

You can include the acceptance criteria in your report. There is a selection in the table properties to include the acceptance criteria and report the value with the formula (Figure 9).

Empower Tips: Include the acceptance criteria and report the value with the formula | Figure 9

Figure 9

 

It’s that easy!

Final Notes: This procedure can be followed using the QuickStart or Pro interface.

 

 

Please rate this Empower Tip of the Week


 

Next week in Empower Tip #73 – Working with the System Suitability Option in Empower (part 6)

 

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