Recent posts

Webinar Highlights: Microfluidics for Macromolecules

By November 14, 2016

Hi, I’m Jim Murphy, Principal Consulting Chemist at Waters, and I recently collaborated with Lucinda (Cohen) Hittle to present an exciting BioanalysisZone webinar on the use of microflow chromatography for macromolecules. Lucinda, a Director of… Read more >

Categories: Pharmaceutical, Technologies
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Tips to maintain your HPLC & UHPLC systems and columns

By October 13, 2016

Recently, Ade Kujore (Cecil Instruments), Tracie Brombos (GenTech Scientific), and I were asked by Angelo De Palma, a well-respected writer for Lab Manager magazine, to contribute to an article about maintaining and caring for your… Read more >

Categories: Technologies

Webinar Highlights: Advanced Techniques in Peptide Isolation

By October 10, 2016

Hello, I’m Andy Aubin, Principal Consulting Chemist at Waters.  Jo-Ann Jablonski, Principal Scientist at Waters, and I recently conducted a webinar that addressed some techniques to make peptide purifications more efficient. We discussed three techniques:… Read more >

Categories: Technologies
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The Waters ACQUITY Arc System Receives 2016 Frost & Sullivan New Product Innovation Award

By October 4, 2016

Bridging the gap between HPLC and UPLC performance, the ACQUITY Arc System is a favorite of QC laboratories that test small and large molecule pharmaceuticals. We’re excited to announce today (Tuesday, Oct. 5) that our… Read more >

Categories: Technologies
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Binary vs. Quaternary: How to Decide Which Pump is Right for You

By September 12, 2016

Well, you’ve made it this far, and I am guessing that you are coming back because I have provided some useful information to help you understand the differences and nuances of a binary versus a… Read more >

Categories: General, Technologies
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Is using Microflow LC in an Industrial Setting Really that Cumbersome?

By August 30, 2016

Microflow or nanoflow chromatography has been used mostly in the academic and fundamental research environment in the past for its various advantages over analytical liquid chromatography, but rarely in the industrial settings. This is most… Read more >

Categories: Pharmaceutical, Technologies
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Microflow LC Offers Better Sensitivity Due to Reduced Matrix Effects!

By August 15, 2016

What are matrix effects? In my last post, “What is Microflow,”  I talked about two main parameters – better sampling efficiency and reduced matrix effects – for microflow LC/MS that result in higher sensitivity than its… Read more >

Categories: Pharmaceutical, Technologies
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The Advantages of a Targeted 2D LC Approach

By August 10, 2016

  Webinar Highlights Focus on the Relevant: The Advantages of a Targeted 2D Chromatography Approach Hi folks, I’m Daniel Root, Senior Product Marketing Manager for Multidimensional LC Systems at Waters. I recently conducted a webinar… Read more >

Categories: Technologies
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Method Scaling in Preparative HPLC: Analytical Method &
Preparative Method

By August 8, 2016

Andrew Aubin (Andy): Manager, Purification / SFx Systems Marketing Laboratory & Blogger VOC: Voice of the Chemist VOC:  “I tried to scale up my analytical HPLC method to prep and it didn’t work.” Andy:  This is… Read more >

Categories: Technologies
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What is microflow LC?

By July 28, 2016
Small Molecule Graph

What are the differences between micro-scale and conventional LC? Microflow (a.k.a. microscale) LC has been widely applied to proteomic research for years. Recently, as microflow LC-MS systems continue to evolve, more and more laboratories in… Read more >

Categories: Technologies
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