Recent posts

Get Empowered: Review Window and the Processing Method | Tip #62, Deriving Channels

By March 28, 2018
Empower tip-of-the-week

#62: In Empower Software, deriving a channel lets us mathematically combine two channels of data. What if we wanted to combine more than two channels? There’s a relatively new feature that lets us combine up to 10 channels of data, called Formula Based Derived Channel. Let’s see how it works.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , ,

Columns Matter, Too: How to Improve Nano and Microflow LC-MS Proteomics by Considering the Separation Itself

By March 22, 2018

Can pairing column stationary phases improve nanoflow and microflow LC-MS results? Let’s take a closer look at the basics of trapping and the advantages and considerations for implementing a trapping step in a LC separation in part 1 of this 3-part series.

Categories: Technologies
Tags: , , , ,

Get Empowered: Review Window and the Processing Method | Tip #61, Deriving Channels

By March 20, 2018
Empower tip-of-the-week

#61: Learn how to derive a channel for Timed Mass for 3D MS data in Empower Software. Timed Mass creates a channel that specifies a mass at specified starting times, which can maximize sensitivity and allow us to perform quantification for all components regardless of the differences in mass.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , ,

What’s Changing Analytical Method Transfer Today? Part 2: Organizations

By March 19, 2018

Is your analytical method bound for the lab down the hall, or the lab halfway around the world? If you’re an analytical or QC scientist, get ready for more method transfers between organizations. We explore the complexities of analytical method transfer in part 2 of our ongoing series.

Categories: Technologies
Tags: , , , , ,

Get Empowered: Review Window and the Processing Method | Tip #60, Deriving Channels

By March 13, 2018
Empower tip-of-the-week

#60. Another option for Deriving Channels in Empower when working with 3D MS data is Total Plot, a 2D chromatogram that plots the sum of all ion intensities acquired across a specified mass range at every time point. It is a subset of the TIC plot, which we covered in Tip 57.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , ,

Get Empowered: Review Window and the Processing Method | Tip #59, Deriving Channels

By March 7, 2018
Empower tip-of-the-week

#59: We previously discussed MaxPlot for 3D PDA data in Tip 52. Today we are going to learn about MaxPlot for 3D MS data. MaxPlot is a 2D chromatogram that plots each time point at the maximum intensity across the mass range.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , ,

Get Empowered: Review Window and the Processing Method | Tip #58, Deriving Channels

By February 27, 2018
Empower tip-of-the-week

#58: In this tip, we will continue the discussion on deriving a total ion chromatogram (TIC) plot from 3D MS data; specifically, how to improve a noisy TIC plot.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , ,

What’s Changing Analytical Method Transfer Today?

By February 23, 2018

There’s a new analytical testing landscape taking shape, and it’s having a big effect on how we develop, transfer, and update methods. Data quality and business efficiency are both at stake. Are you ready?

Categories: Technologies
Tags: , , , , , ,

Get Empowered: Review Window and the Processing Method | Tip #57, Deriving Channels

By February 22, 2018
Empower tip-of-the-week

#57: How to derive a channel in Empower Software when working with 3D mass spec (MS) data, or the Total Ion Chromatogram (TIC), which plots the sum of all ion intensities acquired across the mass range at every time point.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , , ,

Get Empowered: Review Window and the Processing Method | Tip #56, Deriving Channels

By February 14, 2018
Empower tip-of-the-week

#56: If you have an ACQUITY QDa Mass Detector on your HPLC or UPLC instrument and collect 3D MS data, there are a number of options for deriving a channel. In today’s tip, we’ll discuss deriving Single Mass from 3D MS data.

Categories: Empower Tip-of-the-Week, Technologies
Tags: , , , , , , ,