Recent posts

Xevo TQ-GC Tips & Tricks: How to extend MS data collection and reference mass spectral libraries

By December 17, 2018
Xevo TQ-GC System

Available on the Xevo TQ-GC and all Xevo mass spectrometers, RADAR is a simple but powerful acquisition mode that can aid method development, track coextracted interference compounds, and allow re-processing of previously acquired data.

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How Mass Detection Helps a CRO in China Expand its Outsourced Drug Discovery Services

By November 20, 2018

Learn how the ACQUITY QDa Mass Detector brings the power of mass detection for purification to Medicilon, helping this CRO meet the growing demand for outsourced services in the pharmaceutical and biotechnology industries.

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When Resolving Minor Differences in Protein Therapeutics Can Have a Major Impact

By November 6, 2018

Scientists from Waters and Pfizer collaborated to take on the challenge of engineering a novel reversed-phase LC column for high-throughput separations with enhanced resolution, selectivity, and recovery of target mAbs and ADCs.

Categories: Columns, Technologies
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The Quest for a Universal Chromatography Technique

By August 23, 2018

When considering that the range of compounds that might be subject to chromatography goes from highly volatile species with molecular weights of tens of Daltons, to proteins with molecular weights of hundreds of thousands of Daltons, maybe it isn’t so surprising that there are a variety of separation techniques required.

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Columns Matter, Too: Choosing Optimal Conditions for Trap-and-Elute Nanoflow and Microflow LC-MS

By May 14, 2018

Considerations for optimizing trapping conditions, such as flow rate and trapping volume, in nanoscale and microflow LC-MS.

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UPLC Chromatography Gets an Update: Because Science Never Quits

By April 27, 2018

We’ve updated our UPLC systems to enable you to find faster, simpler, and better ways to do your work. Take a closer look at our new and improved ACQUITY UPLC PLUS Series.

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What is Changing Analytical Method Transfer Today? Part 3: Methods Across Borders

By April 23, 2018

One scientist at a major global pharma company estimated that an analytical method could see up to 100 transfers in its lifetime. Increasingly, such transfers will take place across geographic borders. How ready are you to mobilize your methods?

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Columns Matter, Too: Choosing the Best Stationary Phase for NanoFlow and Microflow LC-MS

By April 3, 2018

On the impact of retentivity and characteristics of the stationary phases for reversed-phase proteomic separations and how you can use them to your advantage.

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Columns Matter, Too: How to Improve Nano and Microflow LC-MS Proteomics by Considering the Separation Itself

By March 22, 2018

Can pairing column stationary phases improve nanoflow and microflow LC-MS results? Let’s take a closer look at the basics of trapping and the advantages and considerations for implementing a trapping step in a LC separation in part 1 of this 3-part series.

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What’s Changing Analytical Method Transfer Today? Part 2: Organizations

By March 19, 2018

Is your analytical method bound for the lab down the hall, or the lab halfway around the world? If you’re an analytical or QC scientist, get ready for more method transfers between organizations. We explore the complexities of analytical method transfer in part 2 of our ongoing series.

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