Recent posts

Effective Use of the ACQUITY QDa Mass Detector with Your LC: A Q and A with Dr. Tom Wheat

By January 26, 2016

  I recently presented a webinar describing some techniques and tools used for effectively using the QDa Mass Detector with liquid chromatography systems. Several attendees submitted questions that may be of general interest to a… Read more >

Categories: Pharmaceutical

Resolution in life and mass spectrometers? It really depends…

By January 25, 2016

“How few there are who have courage enough to own their faults, or resolution enough to mend them.” Benjamin Franklin As I sat one morning before work staring into my green tea leaves at the… Read more >

Categories: Pharmaceutical

5 Insights: Protein Quantification Using the Surrogate Peptide Method

By January 19, 2016

What can you get all the top Pharma and CRO’s scientists to agree on? That the biopharma industry is growing and quantifying biotherapeutics for bioanalysis is difficult – but you have options.

Categories: Pharmaceutical, Technologies
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Developing Separation Methods for Natural Products: Questions and Answers from a Webinar with Dr. Tom Wheat

By December 15, 2015

The development of chromatographic methods for natural products is challenging due to the complexity of the sample matrix and analyte chemistry. However, by understanding the fundamental parameters of your chromatography and strategies for efficient detection,… Read more >

Categories: Pharmaceutical
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Is Ion Mobility Mass Spectrometry Child’s Play?

By December 4, 2015

On Wednesday evening after dinner and my usual digestif, I was watching the webcast “Making Ion Mobility Mass Spectrometry Routine” when my son walked by. “Wow dad, that’s kind of cool! What the heck is… Read more >

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Modernizing Traditional Chinese Medicines

By November 23, 2015

Traditional Chinese or herbal medicines (TCM) have been used by patients and doctors for thousands of years. According to a 2006 overview in Toxicologic Pathology, the “documentation of Chinese materia medica (CMM) dates back to… Read more >

Categories: Pharmaceutical
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The Excitement and Frustration of ADCs

By October 8, 2015

Bioanalysis of Antibody Drug Conjugates in the Spotlight Few, if any, of the joggers along Boston’s Charles River could have realized the anticipation contained within the Hyatt Cambridge on a recent September Sunday morning. In… Read more >

Categories: Pharmaceutical, Technologies
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Multiple Attribute Monitoring of Biopharmaceuticals Using Mass Detection

By September 3, 2015

Multiple attribute monitoring has become a hot topic of discussion within biopharmaceutical organizations as the methodology allows detection and measurement of more critical quality attributes than conventional methods. Waters recently sponsored an outstanding webinar on… Read more >

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Microflow LC-MS in Early Discovery through Development

By April 23, 2015

Let’s face it. Microflow LC-MS is a challenge. Only a few do it well, and even fewer do it well consistently. And for those who have had success, their methods can completely fall apart when… Read more >

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Characterizing Extractables from Packaging Materials

By April 9, 2015

Characterization of packaging in various industries has become more important due to ever-increasing global regulations. The first regulations for plastics used in food packaging and contact materials were established in 1982 in Europe1, which have… Read more >

Categories: Chemical, Food & Environmental, Pharmaceutical, Technologies
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