Recent posts

11th ISNS European Regional Meeting, Bratislava Slovakia; An Overview

By October 30, 2018

Reflecting on a common concern in newborn screening: Reliability.

Categories: Clinical
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Advancing Diagnostic Screening with the RenataDX Screening System

By October 11, 2018

Waters’ legacy of purposeful innovation continues with the recently introduced RenataDX Screening System, a flow-injection tandem mass spectrometry system for high-throughput analysis of extracted dried blood spots and other physiological matrices.

Categories: Clinical
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The Historical Role of Mass Spectrometry in Newborn Screening

By September 24, 2018

Newborn screening for inherited metabolic disorders dates to the early 1960s when Dr. Robert Guthrie in Buffalo, New York developed the first screening test for phenylketonuria (or PKU), a metabolic disease in which patients can’t metabolize the amino acid phenylalanine.

Categories: Clinical
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Why Tandem Mass Spec is Essential for Newborn Screening

By September 7, 2018

Mass spectrometry has been game changer in newborn screening because rather than having a single test for a single condition, there was now a technique that provided a single test for a large number of different conditions.

Categories: Clinical
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Reducing the Frequency of Service Engineer Visits for LC-MS Maintenance to Annual Events

By October 6, 2017

Labs like King’s Liver Laboratories in London need to analyze thousands of samples with fast turnaround times, so it’s critical to have reliable LC-MS/MS instrumentation that works every day and provides accurate and precise results.

Categories: Clinical, Customer Stories
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The Importance of Therapeutic Drug Monitoring by LC/MS Through the Lens of Organ Transplantation

By June 29, 2017

Let’s look at the area of organ transplantation as an example of how the TDM field is developing. We look at the progression from immunoassays to LC-MS assays.

Categories: Clinical
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Three Trends Fueling Therapeutic Drug Monitoring (TDM) in Asia

By June 28, 2017

Therapeutic drug monitoring (TDM) is a multi-disciplinary clinical specialty, aimed at improving patient care by monitoring drug concentration levels in blood. It enables adjustment of drug dosage for individuals to improve patient outcomes.

Categories: Clinical
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Mass Spectrometry Makes Cents for UC San Diego Clinical Laboratory

By May 2, 2016

“Fast is fine; but accuracy is everything.” The quote is attributed to the famous Wyatt Earp, a sharpshooter and lawman who, with help from his two brothers, sent three outlaws to their graves in the… Read more >

Categories: Clinical, Customer Stories
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Laboratory Developed Tests: More Oversight, or More Vigilance and Reporting?

By December 1, 2015

U.S. FDA Prepares to Oversee LDTs Recently, the U.S. Food and Drug Administration’s Office of Public Health Strategy and Analysis issued an interesting (and much anticipated) report regarding Laboratory Developed Tests (LDTs). The Agency has… Read more >

Categories: Biomedical Research, Clinical