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Urged on by a voice no one else could hear, Ray Kinsella, played by Kevin Costner in the movie Field of Dreams, cleared a few acres of corn to build a baseball field. Shortly after,… Read more >
In biotherapeutics, the state of glycosylation has a direct and pronounced effect of the structure, stability, serum half-life, immunogeneicity and bioactivity of the molecule, and constitutes a critical quality attribute (CQA). In our study, characterizing and comparing the glycosylation profile of infliximab began by examining the glycosylation profiles from intact and reduced subunit mass data.
Advancements in High-Resolution Analytics for Characterization of Innovator and Biosimilar Therapeutics Part 2: Peptide Analysis of Infliximab
Advancements in High-Resolution Analytics for the Characterization of Innovator and Biosimilar Therapeutics Part 1: Intact Proteins As the pharmaceutical industry continues to evolve its focus from small-molecule drugs to balanced product portfolios that include protein… Read more >
Realizing the Advantages of Ultra-High-Performance Size Exclusion Chromatography (SEC) Compared to GPC Intertek is a global provider of quality and safety services designed to help businesses improve products, assets and processes, overcome market constraints and… Read more >
Targeted LC-MS based assays are increasingly applied in the post-discovery Omics area with an emphasis on validation, the first of many phases in translational research; and in studies that are aimed at gaining the understanding… Read more >
Tips for Making The Analytical Scientist’s Prized PowerList The Analytical Scientist magazine published its PowerList 2016 of the most influential women in the analytical sciences in October. Named to the list was Dr. Isabelle Francois, Business… Read more >
The world is facing an unprecedented convergence of environmental and lifestyle factors that dramatically increase our risk of chronic disease. Global warming, antimicrobial resistance, aging populations, and the prevalence of lifestyle-related illnesses are systematically affecting… Read more >
Developing a Rapid, Routine Method for Extraction and Quantification in Complex Infant Products with UPLC/MS-MS Bisphenol A (BPA) is an additive that is primarily used in the production of polycarbonate plastics and epoxy resins. These… Read more >