#60. Another option for Deriving Channels in Empower when working with 3D MS data is Total Plot, a 2D chromatogram that plots the sum of all ion intensities acquired across a specified mass range at every time point. It is a subset of the TIC plot, which we covered in Tip 57.
#59: We previously discussed MaxPlot for 3D PDA data in Tip 52. Today we are going to learn about MaxPlot for 3D MS data. MaxPlot is a 2D chromatogram that plots each time point at the maximum intensity across the mass range.
To get the most out of recent innovations in biopharma development and QC such as multi-attribute monitoring, it’s time to better connect the systems that manage biopharma data. This series explores the what, the why, and the how of better biopharma data.
#58: In this tip, we will continue the discussion on deriving a total ion chromatogram (TIC) plot from 3D MS data; specifically, how to improve a noisy TIC plot.
There’s a new analytical testing landscape taking shape, and it’s having a big effect on how we develop, transfer, and update methods. Data quality and business efficiency are both at stake. Are you ready?
#57: How to derive a channel in Empower Software when working with 3D mass spec (MS) data, or the Total Ion Chromatogram (TIC), which plots the sum of all ion intensities acquired across the mass range at every time point.
#56: If you have an ACQUITY QDa Mass Detector on your HPLC or UPLC instrument and collect 3D MS data, there are a number of options for deriving a channel. In today’s tip, we’ll discuss deriving Single Mass from 3D MS data.
Q&A from webinar on using targeted 2D LC (RP-RP) for effective impurity analysis to address peak coelutions The Waters pharmacuetical team recently hosted a webinar discussion how two-dimentional LC can offer a solution to analyze… Read more >
#55: Have you ever had a sample where each component had a different lambda max and it was difficult to pick one wavelength to use for quantitation? We show how to use Timed Wavelength when Deriving Channels in Empower Software.
#54: We discuss another option for Deriving Channels in Empower Software when working with photodiode array (PDA) data, called RatioPlot.